Changes in depression and anxiety through mindfulness group therapy in Japan: the role of mindfulness and self-compassion as possible mediators
Toru Takahashi, F. Sugiyama, T. Kikai, I. Kawashima, Siqing Guan, M. Oguchi, Taro Uchida, Hiroaki Kumano
BioPsychoSocial Medicine February 18, 2019 DOI: 10.1186/s13030-019-0145-4 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Pre-post intervention with follow-up Peer reviewed |
|---|---|
| Sample size | 16 |
| Population | People who suffered from depression and/or anxiety in Japan |
| Intervention | Mindfulness group therapy |
| Duration | 8-week intervention, 2-month follow-up |
| Topics | Anxiety Depression Meditation |
| Key points | Depression and anxiety decreased significantly from pre- to post-intervention and follow-up, with moderate to large effect sizes. |
Abstract
BackgroundMindfulness-based interventions are increasingly being implemented worldwide for problems with depression and anxiety, and they have shown evidence of efficacy. However, few studies have examined the effects of a mindfulness-based group therapy based on standard programs for depression and anxiety until follow-up in Japan. This study addresses that gap. Furthermore, this study explored the mechanisms of action, focusing on mindfulness, mind wandering, self-compassion, and the behavioral inhibition and behavioral activation systems (BIS/BAS) as possible mediators.MethodsWe examined 16 people who suffered from depression and/or anxiety in an 8-week mindfulness group therapy. Measurements were conducted using questionnaires on depression and trait-anxiety (outcome variables), mindfulness, mind wandering, self-compassion, and the BIS/BAS (process variables) at pre- and post-intervention and 2-month follow-up. Changes in the outcome and process variables were tested, and the correlations among the changes in those variables were explored.ResultsDepression and anxiety decreased significantly, with moderate to large effect sizes, from pre- to post-intervention and follow-up. In process variables, the observing and nonreactivity facets of mindfulness significantly increased from pre- to post-intervention and follow-up. The nonjudging facet of mindfulness and self-compassion significantly increased from pre-intervention to follow-up. Other facets of mindfulness, mind wandering, and the BIS/BAS did not significantly change. Improvements in some facets of mindfulness and self-compassion and reductions in BIS were significantly correlated with decreases in depression and anxiety.ConclusionsAn 8-week mindfulness group therapy program may be effective for people suffering from depression and anxiety in Japan. Mindfulness and self-compassion may be important mediators of the effects of the mindfulness group therapy. Future studies should confirm these findings by using a control group.Trial registrationUniversity Hospital Medical Information Network (UMIN CTR) UMIN000022966. Registered July 1, 2016, https://upload.umin.ac.jp/cgi-open-bin/ctr/ctr_view.cgi?recptno=R000026425
Comparable studies
Other non-randomized and open-label trials on anxiety, most cited first.
Citations in the library
Cited by 7
- The efficacy of mindfulness-based interventions on mental health among university students: a systematic review and meta-analysis. Frontiers in Public Health 2023
- The Effects of Mindfulness Meditation on Nursing Students' Stress and Anxiety Levels. Nursing Education Perspectives
- A brief online mindfulness intervention: study protocol for Indonesian undergraduate students, a randomized controlled trial. Trials May 13, 2025
- Effects of mindfulness-based stress reduction on ICU nurses' resilience and well-being. Intensive & critical care nursing November 23, 2025
- Impact of mindfulness-based and health self-management interventions on mindfulness, self-compassion, and physical activity in older adults with subjective cognitive decline: A secondary analysis of the SCD-Well randomized controlled trial. Alzheimer S and Dementia Diagnosis Assessment and Disease Monitoring 2024
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- Mindfulness-based interventions for psychiatric disorders: A systematic review and meta-analysis. Clinical Psychology Review February 1, 2018
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