Skip to content

The Effect of Mindfulness-Based Therapy on Anxiety and Depression: A Meta-Analytic Review

Stefan G Hofmann, Alice T. Sawyer, Ashley A. Witt, Diana Oh

Journal of Consulting and Clinical Psychology April 1, 2010 DOI: 10.1037/a0018555 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Meta-analysis Peer reviewed
Sample size 1,140
Population Clinical samples with conditions including cancer, generalized anxiety disorder, depression, and other psychiatric or medical conditions
Intervention mindfulness-based therapy
Topics Anxiety Depression Meditation
Key findings Mindfulness-based therapy was moderately effective for improving anxiety and mood symptoms in clinical populations, with larger effects in patients with anxiety and mood disorders.

Abstract

Background: Although mindfulness-based therapy has become a popular treatment, little is known about its efficacy.

Objectives: To conduct an effect size analysis of this popular intervention for anxiety and mood symptoms in clinical samples. DATA SOURCES A literature search was conducted using PubMed, PsycInfo, the Cochrane Library, and manual searches. REVIEW METHODS The search identified 39 studies totaling 1,140 participants receiving mindfulness-based therapy for a range of conditions, including cancer, generalized anxiety disorder, depression, and other psychiatric or medical conditions.

Results: Effect size estimates suggest that mindfulness-based therapy was moderately effective for improving anxiety (Hedges’ g = 0.63) and mood symptoms (Hedges’ g = 0.59) from pre to post-treatment in the overall sample. In patients with anxiety and mood disorders, this intervention was associated with effect sizes (Hedges’ g) of 0.97 and 0.95 for improving anxiety and mood symptoms, respectively. These effect sizes were robust, unrelated to publication year or number of treatment sessions, and were maintained over follow-up.

Conclusion: These results suggest that mindfulness-based therapy is a promising intervention for treating anxiety and mood problems in clinical populations.

Comparable studies

Other systematic reviews and meta-analyses on anxiety, most cited first.

Study Year Design Participants
Meditation Programs for Psychological Stress and Well-being Diverse adult clinical populations 2014 Meta-analysis n = 3,515
Research Review: The effects of mindfulness‐based interventions on cognition and mental health in children and adolescents – a meta‐analysis of randomized controlled trials Children and adolescents 2018 Systematic review and meta-analysis n = 3,666
Therapeutic effects of classic serotonergic psychedelics: A systematic review of modern‐era clinical studies Patients with cancer- or illness-related anxiety and depression, major depressive... 2020 Systematic review n = 188
Does Mindfulness Meditation Improve Anxiety and Mood Symptoms? A Review of the Controlled Research Clinical populations with medical and emotional disorders 2007 Systematic review n = 15
Antidepressive, anxiolytic, and antiaddictive effects of ayahuasca, psilocybin and lysergic acid diethylamide (LSD): a systematic review of clinical trials published in the last 25 years Patients from included clinical trials 2016 Systematic review

Citations in the library

Cited by 912

and 907 more in the library

Cites 45

and 40 more in the library

Explore topics