Mindfulness-Based Stress Reduction Program to Improve Well-Being and Health in Healthcare Professionals.
Marco Marotta, Niccolo Grassi, Alessandro Pingitore, Alessandra Parlanti, Sergio Berti, Cristina Vassalle
Journal of Clinical Medicine October 28, 2025 DOI: 10.3390/jcm14217655 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Quasi-experimental pre-post study Peer reviewed |
|---|---|
| Population | Italian health-care professionals |
| Intervention | Mindfulness-Based Stress Reduction (MBSR) program |
| Topics | Meditation |
| Keywords | Mbi Pgwbi Pss Cardiovascular risk Care quality Distress Dyslipidemia Healthcare workers Prevention Psycho-emotional status Well-being |
| Key findings | After an MBSR program, health-care professionals showed significant improvements in psychological well-being, perceived stress, burnout dimensions, and lipid profile. |
Abstract
Aim: To evaluate basal well-being and the effects of a Mindfulness-Based Stress Reduction (MBSR) program in health-care professionals (HCPs), a recognized worker category subjected to elevated stress from job conditions.
Methods: A quasi-experimental pre-post study was conducted in Italian HCPs. Well-being (assessed by Psychological General Well-Being Index-PGWBI), stress (Perceived Stress Scale-PSS), and burnout (Maslach Burnout Inventory-MBI) were collected at baseline and after an MBSR program. Moreover, levels of C reactive protein, glucose, and lipid profiles were also monitored in a subgroup.
Results: At baseline, Total-PGWBI score value evidenced no distress, whereas Total-PSS and MBI dimensions (emotional exhaustion-EE, depersonalization and detachment from the job-DP, and lack of personal or professional accomplishment-PA) indicate moderate distress. After MBSR, PGWBI, PSS, and MBI dimensions significantly improved. Moreover, significant benefits on lipid profile were observed after MBSR.
Conclusions: MBSR may be a promising method to improve well-being and lipid profile in HCPs. Thus, MBSR might represent a new future complementary prevention tool for mental and physical health maintenance in this category of workers.
Comparable studies
Other non-randomized and open-label trials on meditation, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| Mindfulness-Based Stress Reduction in Relation to Quality of Life, Mood, Symptoms of Stress, and Immune Parameters in Breast and Prostate Cancer Outpatients Early-stage breast and prostate cancer patients | 2003 | Pre-post intervention study | n = 59 |
| Exploring self‐compassion and empathy in the context of mindfulness‐based stress reduction (MBSR) Community sample | 2010 | Pre-post intervention study | |
| Mindfulness-Based Stress Reduction Lowers Psychological Distress In Medical Students Second-year medical students | 2003 | Prospective nonrandomized cohort-controlled study | n = 302 |
| Intensive meditation training, immune cell telomerase activity, and psychological mediators. Retreat participants and matched controls | 2011 | Controlled trial with wait-list control group | n = 60 |
| The Effectiveness of Mindfulness Training for Children with ADHD and Mindful Parenting for their Parents Children aged 8-12 with ADHD and their parents | 2011 | Within-group waitlist controlled trial | n = 22 |
Citations in the library
Cites 21
- Women Benefit More Than Men in Response to College-based Meditation Training. Frontiers in Psychology 2017
- Effect of mindfulness-based interventions on people with prehypertension or hypertension: a systematic review and meta-analysis of randomized controlled trials. BMC cardiovascular disorders February 14, 2024
- A systematic review of mindfulness-based interventions to reduce ICU nurse burnout: global evidence and thematic synthesis. BMC Nursing July 15, 2025
- The effect of mindfulness training on the psychological state of high-level athletes: Meta analysis and system evaluation research. Journal of Sports Sciences March 1, 2025
- Which type and dosage of mindfulness-based interventions are most effective for chronic pain? A systematic review and network meta-analysis. Journal of Psychosomatic Research April 1, 2025
and 16 more in the library