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Mindfulness-Based Stress Reduction Program to Improve Well-Being and Health in Healthcare Professionals.

Marco Marotta, Niccolo Grassi, Alessandro Pingitore, Alessandra Parlanti, Sergio Berti, Cristina Vassalle

Journal of Clinical Medicine October 28, 2025 DOI: 10.3390/jcm14217655 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Quasi-experimental pre-post study Peer reviewed
Population Italian health-care professionals
Intervention Mindfulness-Based Stress Reduction (MBSR) program
Topics Meditation
Keywords Mbi Pgwbi Pss Cardiovascular risk Care quality Distress Dyslipidemia Healthcare workers Prevention Psycho-emotional status Well-being
Key findings After an MBSR program, health-care professionals showed significant improvements in psychological well-being, perceived stress, burnout dimensions, and lipid profile.

Abstract

Aim: To evaluate basal well-being and the effects of a Mindfulness-Based Stress Reduction (MBSR) program in health-care professionals (HCPs), a recognized worker category subjected to elevated stress from job conditions.

Methods: A quasi-experimental pre-post study was conducted in Italian HCPs. Well-being (assessed by Psychological General Well-Being Index-PGWBI), stress (Perceived Stress Scale-PSS), and burnout (Maslach Burnout Inventory-MBI) were collected at baseline and after an MBSR program. Moreover, levels of C reactive protein, glucose, and lipid profiles were also monitored in a subgroup.

Results: At baseline, Total-PGWBI score value evidenced no distress, whereas Total-PSS and MBI dimensions (emotional exhaustion-EE, depersonalization and detachment from the job-DP, and lack of personal or professional accomplishment-PA) indicate moderate distress. After MBSR, PGWBI, PSS, and MBI dimensions significantly improved. Moreover, significant benefits on lipid profile were observed after MBSR.

Conclusions: MBSR may be a promising method to improve well-being and lipid profile in HCPs. Thus, MBSR might represent a new future complementary prevention tool for mental and physical health maintenance in this category of workers.

Comparable studies

Other non-randomized and open-label trials on meditation, most cited first.

Study Year Design Participants
Mindfulness-Based Stress Reduction in Relation to Quality of Life, Mood, Symptoms of Stress, and Immune Parameters in Breast and Prostate Cancer Outpatients Early-stage breast and prostate cancer patients 2003 Pre-post intervention study n = 59
Exploring self‐compassion and empathy in the context of mindfulness‐based stress reduction (MBSR) Community sample 2010 Pre-post intervention study
Mindfulness-Based Stress Reduction Lowers Psychological Distress In Medical Students Second-year medical students 2003 Prospective nonrandomized cohort-controlled study n = 302
Intensive meditation training, immune cell telomerase activity, and psychological mediators. Retreat participants and matched controls 2011 Controlled trial with wait-list control group n = 60
The Effectiveness of Mindfulness Training for Children with ADHD and Mindful Parenting for their Parents Children aged 8-12 with ADHD and their parents 2011 Within-group waitlist controlled trial n = 22

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