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Relationship between perceived stress and death anxiety with mediating role of self-transcendence among older patients with myocardial infarction.

Seyed Mohammadreza Hosseini, Fatemeh Mohammadi, Zahra Hosseinkhani, Seyedeh Ameneh Motalebi

BMC Psychology December 26, 2025 DOI: 10.1186/s40359-025-03897-1 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Descriptive and correlational study Peer reviewed
Sample size 252
Population Older patients with myocardial infarction
Topics Anxiety
Keywords Aged Death anxiety Myocardial infarction Perceived stress Self-transcendence
Key points Perceived stress was significantly associated with death anxiety, and self-transcendence mediated this relationship.

Abstract

Death anxiety represents a persistent form of anxiety experienced by patients with Myocardial Infarction (MI), even after receiving medical treatment. Recognizing the critical role of self-transcendence in managing emotions and anxiety, this study aims to investigate the relationship between perceived stress and death anxiety with the mediating role of self-transcendence among older patients with MI. This descriptive and correlational study, conducted in 2023, included 252 older patients with MI. Participants were selected through a convenience sampling method. Data was collected using the Templer Death Anxiety Scale, the Cohen Perceived Stress Scale, and the Reed Self-Transcendence questionnaires. Structural equation modeling (SEM) was employed to examine the mediating role of self-transcendence in the relationship between perceived stress and death anxiety. The study comprised 252 older patients with a mean age of 66.98 ± 6.92 years. The majority of participants were male (n = 188, 74.6%) and married (n = 191, 75.8%). The mean scores for perceived stress, death anxiety, and self-transcendence were 29.48 ± 4.30, 8.86 ± 3.28, and 41.81 ± 6.29, respectively. The results of SEM analysis revealed a significant association between perceived stress and death anxiety (β = 0.16, P = 0.04), with self-transcendence playing a mediating role (β = 0.20, P < 0.001), in this relationship. Based on the mediating role of self-transcendence, clinically, healthcare providers should assess for and facilitate self-transcendent practices as a component of routine cardiac rehabilitation. Policymakers and program directors should fund and integrate evidence-based interventions like meaning-centered psychotherapy or mindfulness-based stress reduction, which are known to cultivate self-transcendence, into standard post-MI care pathways to directly target the reduction of death anxiety.

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