The neuroscience of spirituality, religion, and mental health: A systematic review and synthesis.
David H Rosmarin, Caroline C Kaufman, Stephanie Friree Ford, Poorvi Keshava, Mia Drury, Sean Minns, Cheri Marmarosh, Avijit Chowdhury, Matthew D. Sacchet
Journal of Psychiatric Research December 1, 2022 DOI: 10.1016/j.jpsychires.2022.10.003 (opens in new tab) via PubMed
Summary
AI-generated from the abstractA systematic review of 18 studies that simultaneously examined spirituality/religion (S/R), mental health, and neurobiology found that most studies were of moderate to high methodological quality. The review highlights the need for more research in this area, particularly studies that use validated assessments of S/R. The findings address the neurobiological correlates of S/R in relation to depression, anxiety, alcohol/substance misuse, and psychosis, but the relationships across all three domains remain unclear.
Study at a glance
| Characteristics | Systematic review Peer reviewed |
|---|---|
| Sample size | 18 |
| Population | Studies concurrently examining S/R, mental health, and neurobiology |
| Topics | Anxiety Depression |
| Keywords | Alcohol abuse Neurobiology Religion |
| Key finding | Most studies demonstrated moderate to high methodological quality, and the review highlights the need for additional studies with validated assessment of S/R. |
Abstract
Prior research highlights the importance of spirituality/religion (S/R) as it relates to several aspects of mental health and clinical interventions. This research has been expanded to include the concurrent examination of neurobiological correlates of S/R to elucidate potential biological mechanisms. However, the majority of neurobiological research on S/R has neglected mental health, and the relationship across all three of these domains (S/R, mental health, and neurobiology) remains unclear. This study systematically reviewed research concurrently examining S/R, mental health, and neurobiology, and rated the methodological quality of included studies. Eighteen identified studies were then included in an integrated literature review and discussion, regarding the neurobiological correlates of S/R as it pertains to depression, anxiety, alcohol/substance misuse, and psychosis. The majority of studies demonstrated moderate to high methodological quality. Findings highlight the need for additional studies in this area as well as research that includes validated assessment of S/R.