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Mindfulness Meditation for Chronic Pain: Systematic Review and Meta-analysis

Lara Hilton, Susanne Hempel, Brett A. Ewing, Eric Apaydin, Lea Xenakis, Sydne J Newberry, Benjamin Colaiaco, A. R. Maher, Roberta M Shanman, Melony E. Sorbero, Margaret Maglione

Annals of Behavioral Medicine September 22, 2016 DOI: 10.1007/s12160-016-9844-2 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Systematic review with meta-analysis Randomized Peer reviewed
Population Adults with chronic pain
Intervention Mindfulness meditation
Topics Meditation
Key findings Mindfulness meditation is associated with a small decrease in pain and improvements in depression symptoms and quality of life in adults with chronic pain, based on low-quality evidence.

Abstract

BackgroundChronic pain patients increasingly seek treatment through mindfulness meditation.PurposeThis study aims to synthesize evidence on efficacy and safety of mindfulness meditation interventions for the treatment of chronic pain in adults.MethodWe conducted a systematic review on randomized controlled trials (RCTs) with meta-analyses using the Hartung-Knapp-Sidik-Jonkman method for random-effects models. Quality of evidence was assessed using the GRADE approach. Outcomes included pain, depression, quality of life, and analgesic use.ResultsThirty-eight RCTs met inclusion criteria; seven reported on safety. We found low-quality evidence that mindfulness meditation is associated with a small decrease in pain compared with all types of controls in 30 RCTs. Statistically significant effects were also found for depression symptoms and quality of life.ConclusionsWhile mindfulness meditation improves pain and depression symptoms and quality of life, additional well-designed, rigorous, and large-scale RCTs are needed to decisively provide estimates of the efficacy of mindfulness meditation for chronic pain.

Comparable studies

Other systematic reviews and meta-analyses on meditation, most cited first.

Study Year Design Participants
Meditation Programs for Psychological Stress and Well-being Diverse adult clinical populations 2014 Meta-analysis n = 3,515
Mindfulness-Based Stress Reduction for Stress Management in Healthy People: A Review and Meta-Analysis Healthy subjects 2009 Systematic review and meta-analysis
The psychological effects of meditation: A meta-analysis. Nonclinical groups of adult meditators 2012 Meta-analysis n = 163
Efficacy of Mindfulness-Based Cognitive Therapy in Prevention of Depressive Relapse Adults with recurrent depression in full or partial remission 2016 Meta-analysis of individual patient data from randomized controlled trials n = 1,258
Mindfulness‐Based Stress Reduction and Mindfulness‐Based Cognitive Therapy – a systematic review of randomized controlled trials 2011 Systematic review

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