Perceived Impact of Psychedelics on Sexual, Gender, and Intimate Relationship Dynamics: A Mixed-Methods Investigation
Daniel J. Kruger, Eirini K. Argyri, Justin K. Mogilski, Moss Herberholz, Julie Barron, Jacob S. Aday, Kevin F. Boehnke
The Journal of Sex Research March 28, 2025 DOI: 10.1080/00224499.2025.2479197 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Survey Peer reviewed |
|---|---|
| Sample size | 581 |
| Population | Participants who reported psychedelic experiences |
| Keywords | Human sexuality Openness to experience Sexual attraction Sexual desire Clinical psychology Developmental psychology Sexual behavior Gender studies |
| Citations | 7 |
| Key findings | Psychedelic experiences were associated with enhanced relationship quality, attraction to partners, and sexual activities, as well as changes in gender identity and sexual attraction. |
Abstract
= 581). Most participants (70.2%) reported perceived impacts of psychedelic experiences on their sexuality and/or sexual experiences, with 65.4% noting short-term effects during psychedelic experiences and 52.8% reporting long-term effects, although no individual effect was endorsed by most participants. A higher proportion of participants indicated that psychedelic experiences enhanced, rather than diminished, relationship quality, attraction to current partners, and sexual activities. Approximately 10% of participants reported that psychedelic experiences influenced their gender identity and/or expression, reporting increased authenticity, self-acceptance, openness, and freedom in self-expression, as well as altered experiences of sexuality and gender. One-quarter of women and one-eighth of men reported heightened same-sex attraction following psychedelic use, and one-third of those with other gender identities reported changes in sexual attraction. Higher proportions of participants reported dating multiple people, being polyamorous or in an open relationship, or being committed to only one person after their psychedelic experiences compared to before. Regression models identified various perceived effects associated with using large psychedelic doses, more frequent psychedelic use, lower household income, identifying as gender diverse, and especially younger age and identifying as women. Psychedelics may facilitate these changes via self-insight, greater connectedness with others, and increases in self-compassion, though further research is needed.
Citations in the library
Cited by 7
- Unequal representation? A cross-sectional analysis of age, sex, race, and ethnicity in clinical trials of classic psychedelics Journal of Psychopharmacology July 11, 2025
- Extended difficulties after psychedelic experiences: Prevalence and associations in a global, multilingual sample. Research Square April 8, 2026
- Classic Psychedelics for Chronic Pain: A Critical Review of the Literature and Practical Advice for Clinicians. Drugs June 4, 2026
- Psychedelic Use and Psychological Healing Among Gender Exploring Clients: Clinicians’ Perspectives Women & Therapy May 12, 2026
- Major life changes following psychedelic use: A retrospective survey among people using psychedelics naturalistically Scientific Reports April 15, 2026
and 2 more in the library
Cites 49
- REBUS and the Anarchic Brain: Toward a Unified Model of the Brain Action of Psychedelics Pharmacological Reviews June 20, 2019
- The Subjective Effects of Psychedelics Are Necessary for Their Enduring Therapeutic Effects. ACS Pharmacology & Translational Science December 10, 2020
- Predicting Responses to Psychedelics: A Prospective Study Frontiers in Pharmacology November 2, 2018
- Psychedelics reopen the social reward learning critical period Nature June 14, 2023
- Adverse effects of psychedelics: From anecdotes and misinformation to systematic science. Journal of Psychopharmacology February 2, 2022
and 44 more in the library