Low-dose ketamine safely reduces acute pain in the ED with a more rapid and shorter effect than morphine.
Annals of Internal Medicine April 1, 2024 DOI: 10.7326/J24-0017 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Meta-analysis Randomized Peer reviewed |
|---|---|
| Population | Patients with acute pain in the emergency department |
| Interventions | Low-dose ketamine Morphine |
| Topics | Esketamine Ketamine |
| Keywords | Pain management Emergency medicine Ketamine therapy Analgesics Clinical trials |
| Key findings | Low-dose ketamine provides comparable pain relief to morphine for acute pain in the emergency department but with a different side effect profile. |
Abstract
Guo J, Zhao F, Bian J, et al. Low-dose ketamine versus morphine in the treatment of acute pain in the emergency department: a meta-analysis of 15 randomized controlled trials. Am J Emerg Med. 2024;76:140-149. 38071883.