Overmystifying the Psychedelic Experience
Jack D. C. Dahan, Jasper B. Zantvoord, Anja Lok, Karel W. F. Scheepstra
JAMA Psychiatry 2026 DOI: 10.1001/jamapsychiatry.2025.3032 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Theoretical or philosophical paper Peer reviewed |
|---|---|
| Key points | Argues that rigorous investigation of both neurobiological changes and subjective experiences is necessary for understanding psychedelic phenomena. |
Abstract
This Viewpoint addresses the dual domains of psychedelic experience—neurobiological changes and subjective experience—and argues for rigorous investigation of both domains.
Citations in the library
Cites 9
- REBUS and the Anarchic Brain: Toward a Unified Model of the Brain Action of Psychedelics Pharmacological Reviews June 20, 2019
- Psychedelic effects of psilocybin correlate with serotonin 2A receptor occupancy and plasma psilocin levels Neuropsychopharmacology January 26, 2019
- Psilocybin's lasting action requires pyramidal cell types and 5-HT2A receptors. Nature June 1, 2025
- Acute Mood-Elevating Properties of Microdosed Lysergic Acid Diethylamide in Healthy Volunteers: A Home-Administered Randomized Controlled Trial. Biological Psychiatry September 15, 2023
- Extended-release ketamine tablets for treatment-resistant depression: a randomized placebo-controlled phase 2 trial. Nature Medicine July 1, 2024
and 4 more in the library