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Overmystifying the Psychedelic Experience

Jack D. C. Dahan, Jasper B. Zantvoord, Anja Lok, Karel W. F. Scheepstra

JAMA Psychiatry 2026 DOI: 10.1001/jamapsychiatry.2025.3032 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Theoretical or philosophical paper Peer reviewed
Key points Argues that rigorous investigation of both neurobiological changes and subjective experiences is necessary for understanding psychedelic phenomena.

Abstract

This Viewpoint addresses the dual domains of psychedelic experience—neurobiological changes and subjective experience—and argues for rigorous investigation of both domains.