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Overmystifying the Psychedelic Experience

Jack D. C. Dahan, Jasper B. Zantvoord, Anja Lok, Karel W. F. Scheepstra

JAMA Psychiatry January 1, 2026 DOI: 10.1001/jamapsychiatry.2025.3032 (opens in new tab)

Summary

AI-generated from the abstract

A rigorous investigation of psychedelic experience requires studying both its neurobiological changes and its subjective dimensions, as these two domains are equally important for understanding the full effects of psychedelics.

Study at a glance

Characteristics Theoretical or philosophical paper Peer reviewed
Key finding Argues that rigorous investigation of both neurobiological changes and subjective experiences is necessary for understanding psychedelic phenomena.

Abstract

This Viewpoint addresses the dual domains of psychedelic experience—neurobiological changes and subjective experience—and argues for rigorous investigation of both domains.

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