Phencyclidine (PCP) abuse. A close-up look at a growing problem.
S O Isaacs, P Martin, J A Washington
Oral surgery, oral medicine, and oral pathology February 1, 1986 DOI: 10.1016/0030-4220(86)90171-4 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Peer reviewed |
|---|---|
| Key points | PCP intoxication can cause extreme violence, psychosis, and fatal interactions with certain drugs. |
Abstract
PCP or "angel dust" is a dissociative anesthetic agent with notoriety as an abuse substance. Numerous members of many subcultures are frequent users of this drug. It is well known in California's psychedelia, along the East Coast, and in the middle- and working-class suburbs of the Midwest. It is important that practitioners become acquainted with the drug and its effects. Persons intoxicated with PCP have murdered their own children and have even jumped out of high-rise apartment buildings. States of florid psychosis lasting for days can follow a brief encounter with PCP. Inadvertent administration of narcotics and barbiturates to patients with acute PCP intoxication can lead to a crisis that could prove to be fatal.
Citations in the library
Cited by 4
- Absorption, Distribution, Metabolism and Excretion Pharmacogenomics of Drugs of Abuse Pharmacogenomics February 1, 2011
- The dopaminergic alterations induced by 4‐F‐PCP and 4‐Keto‐PCP may enhance their drug‐induced rewarding and reinforcing effects: Implications for abuse Addiction Biology July 1, 2021
- Evaluating the abuse potential of psychedelic drugs as part of the safety pharmacology assessment for medical use in humans. Neuropharmacology November 2018
- Functional changes in neuronal systems induced by phencyclidine administration. Annals of the New York Academy of Sciences October 31, 1996