Cannabis-induced depersonalization disorder in adolescence.
Franziska Hürlimann, Stephan Kupferschmid, Andor E Simon
Neuropsychobiology 2012 DOI: 10.1159/000334605 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Case series Case report Peer reviewed |
|---|---|
| Sample size | 6 |
| Population | Adolescents who developed persistent depersonalization disorder after consuming cannabis |
| Topics | Cannabis |
| Key findings | Six adolescents developed persistent depersonalization disorder after cannabis use, with two cases being severely disabling. |
Abstract
We present a case series of 6 patients who developed persistent depersonalization disorder in adolescence after consuming cannabis. In 2 of these cases, the illness course was severely disabling. Within the growing body of literature that investigates the effects of cannabis use on mental health, the association between cannabis and depersonalization disorder is widely neglected. We review the clinical characteristics of this disorder and summarize the neurobiological evidence relating it to cannabis use. This case series extends awareness about the potentially detrimental effect of cannabis use in young individuals beyond its well-documented relationship with psychosis and other psychological sequelae.
Comparable studies
Other case reports and case series on cannabis, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| Psychotic Reactions Following Cannabis Use in East Indians Patients at an Indian drug addiction clinic who developed acute cannabis-related psychosis | 1974 | Descriptive report (case series of clinical observations) | n = 200 |
| Psychiatric effects of cannabis use Swedish cases of cannabis psychosis | 1985 | Case series | n = 70 |
| Forty-Six Cases of Psychosis in Cannabis Abusers Gunila Bernhardson Habitual cannabis users treated for psychosis at Swedish psychiatric clinics and mental... | 1972 | Case series (retrospective survey of psychiatric records) | n = 46 |
| Hallucinogen persisting perception disorder after psilocybin consumption: a case study 18-year-old man with HPPD after mixed psilocybin and cannabis intoxication | 2005 | Case study | n = 1 |
| Cannabis‐induced Koro in Americans American men aged 22-26 with years of cannabis experience who reported negative... | 2001 | Case series | n = 3 |
Citations in the library
Cited by 6
- Depersonalization-derealization Disorder in Men Health of Man December 28, 2023
- Dissociation in patients with epilepsy and functional seizures: A narrative review of the literature. Seizure June 24, 2023
- THC and CBD: Villain versus Hero? Insights into Adolescent Exposure. International Journal of Molecular Sciences March 9, 2023
- Anomalous Self-Experiences: Markers of Schizophrenia Vulnerability or Symptoms of Depersonalization Disorder? A Phenomenological Investigation of Two Cases. Psychopathology 2018
- Cannabis Induced Psychopathology March 28, 2017
and 1 more in the library
Cites 10
- Causal association between cannabis and psychosis: examination of the evidence The British Journal of Psychiatry January 30, 2004
- Depersonalization: a selective impairment of self-awareness. Consciousness and Cognition March 2011
- Adolescent brain maturation, the endogenous cannabinoid system and the neurobiology of cannabis-induced schizophrenia. Progress in Neurobiology November 2010
- Impact of cannabidiol on the acute memory and psychotomimetic effects of smoked cannabis: naturalistic study: naturalistic study [corrected]. The British Journal of Psychiatry October 2010
- Is depersonalization disorder initiated by illicit drug use any different? A survey of 394 adults. The Journal of Clinical Psychiatry October 1, 2009
and 5 more in the library