Risk factors for cannabis use disorders and cannabis psychosis in Japan: Second report of a survey on cannabis-related health problems among community cannabis users using social networking services.
Yuji Masataka, Takeshi Sugiyama, Yoshiyuki Akahoshi, Toshihiko Matsumoto
Neuropsychopharmacology Reports March 1, 2023 DOI: 10.1002/npr2.12307 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Cross-sectional survey Peer reviewed |
|---|---|
| Sample size | 3,142 |
| Population | Japanese users of social network services who had used cannabis within the preceding year |
| Topics | Cannabis |
| Keywords | Japan Marijuana abuse Mental health Psychotic disorders |
| Key findings | Risk factors for cannabis use disorders include younger age of initiation, family history of mental health problems, pre-existing psychiatric disorders, and use of non-dry-flower cannabis products; for cannabis psychosis, younger initiation and family history of mental health problems are risk factors. |
Abstract
To determine the risk factors for cannabis use disorders and cannabis psychosis in Japan based on a 2021 online survey among Japanese users of social network services. The 3142 respondents who had used cannabis within the preceding year were categorized into two groups based on the development of cannabis use disorder and/or cannabis psychosis. Analyses were performed to determine these conditions' risk factors. Multivariate analysis revealed that factors significantly associated with cannabis use disorders were "cannabis-use initiation at a young age" (p = 0.004, OR: 0.951, 95% CI [0.920-0.984]), "family history of mental health problems" (p < 0.001, OR: 1.988, 95% CI [1.545-2.556]), "psychiatric disorders preceding cannabis use" (p = 0.039, OR: 1.672, 95% CI [1.026-2.722]), and "use of cannabis products other than dry flower" (p < 0.001, OR: 2.725, 95% CI [1.844-4.026]). Factors significantly associated with cannabis psychosis were "cannabis-use initiation at a young age" (p = 0.011, OR: 0.888, 95% CI [0.811-0.973]) and "family history of mental health problems" (p = 0.002, OR: 2.531, 95% CI [1.400-4. 576]). Risk factors for problematic cannabis use were cannabis initiation at a young age, pre-cannabis psychiatric disorders, family history of mental health problems, and the use of cannabis products other than dry flower. However, the causal relationship among these factors remains ambivalent.
Comparable studies
Other cross-sectional and survey studies on cannabis, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| Cannabis use before age 15 and subsequent executive functioning 104 chronic cannabis users (49 early-onset before age 15, 55 late-onset after age 15)... | 2011 | Observational cross-sectional study | n = 148 |
| Patterns of simultaneous polysubstance use in drug using university students Drug-using university students | 2006 | Cross-sectional survey | n = 149 |
| Persisting Reductions in Cannabis, Opioid, and Stimulant Misuse After Naturalistic Psychedelic Use: An Online Survey Online survey respondents | 2020 | Cross-sectional survey | |
| User perceptions of the benefits and harms of hallucinogenic drug use: A web-based questionnaire study Users of hallucinogenic drugs who completed a web-based questionnaire | 2010 | Cross-sectional survey | n = 600 |
| Illicit Use of LSD or Psilocybin, but not MDMA or Nonpsychedelic Drugs, is Associated with Mystical Experiences in a Dose-Dependent Manner Adults recruited from the MAPS website and newsletter, most reporting use of various... | 2012 | Cross-sectional survey | n = 337 |
Citations in the library
Cites 5
- Age-related differences in the impact of cannabis use on the brain and cognition: a systematic review European Archives of Psychiatry and Clinical Neuroscience January 24, 2019
- Risk-thresholds for the association between frequency of cannabis use and the development of psychosis: a systematic review and meta-analysis Psychological Medicine March 24, 2022
- Risk factors for the onset of dependence and chronic psychosis due to cannabis use: Survey of patients with cannabis‐related psychiatric disorders Neuropsychopharmacology Reports September 7, 2020
- Cannabis and synaptic reprogramming of the developing brain. Nature Reviews Neuroscience July 2021
- AKT1 genotype moderates the acute psychotomimetic effects of naturalistically smoked cannabis in young cannabis smokers. Translational Psychiatry February 16, 2016