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Identification of Psychoplastogenic N,N-Dimethylaminoisotryptamine (isoDMT) Analogues through Structure-Activity Relationship Studies.

J Med Chem January 24, 2020 DOI: 10.1021/acs.jmedchem.9b01404 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Structure-activity relationship study Peer reviewed
Key points Specific structural modifications to the isoDMT scaffold can yield analogues with psychoplastogenic activity comparable to or greater than known compounds.

Abstract

Identification of Psychoplastogenic N,N-Dimethylaminoisotryptamine (isoDMT) Analogues through Structure-Activity Relationship Studies.