Transient Stimulation with Psychoplastogens Is Sufficient to Initiate Neuronal Growth
ACS Pharmacology & Translational Science September 11, 2020 Calvin Ly, Alexandra C. Greb, Maxemiliano V. Vargas et al. 127 citations
Cortical neuron atrophy is a hallmark of depression and includes neurite retraction, dendritic spine loss, and decreased synaptic density. Psychoplastogens, small molecules capable of rapidly promoting cortical neuron growth, have been hypothesized to produce long-lasting positive effects on behavior by rectifying these deleterious structural and functional changes. Here we demonstrate that...