Head-twitch response in rodents induced by the hallucinogen 2,5-dimethoxy-4-iodoamphetamine: a comprehensive history, a re-evaluation of mechanisms, and its utility as a model.

Drug Test Anal April 19, 2012 DOI: 10.1002/dta.1333 (opens in new tab)

Study at a glance

AI-extracted from the abstract

Characteristics	Review Peer reviewed
Key findings	The head-twitch response remains a useful but imperfect model for studying hallucinogen mechanisms, with 5-HT2A receptor activation as its primary driver.

Abstract

Head-twitch response in rodents induced by the hallucinogen 2,5-dimethoxy-4-iodoamphetamine: a comprehensive history, a re-evaluation of mechanisms, and its utility as a model.

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Study at a glance

Abstract

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