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DMT use in Cluster Headache: Interim Analysis of an International Survey (S23.003)

Emmanuelle A. D. Schindler, Kevin Lenaburg, Robert Wold

Neurology June 9, 2026 DOI: 10.1212/wnl.0000000000215894 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Survey Peer reviewed
Population Adults with cluster headache
Topics DMT
Keywords Cluster spacecraft Interim analysis Medline Environmental health
Key findings Adults with cluster headache use DMT as a treatment, with some reporting benefits.

Abstract

To carry out a survey on N,N-dimethyltryptamine (DMT) use in adults with cluster headache.

Comparable studies

Other cross-sectional and survey studies on DMT, most cited first.

Study Year Design Participants
Survey of subjective "God encounter experiences": Comparisons among naturally occurring experiences and those occasioned by the classic psychedelics psilocybin, LSD, ayahuasca, or DMT Adults reporting a single most memorable God encounter experience, either nondrug or... 2019 Cross-sectional survey n = 4,285
Survey of entity encounter experiences occasioned by inhaled N,N-dimethyltryptamine: Phenomenology, interpretation, and enduring effects. People who had a memorable entity encounter after taking N,N-dimethyltryptamine 2020 Survey n = 2,561
5-methoxy-N,N-dimethyltryptamine (5-MeO-DMT) used in a naturalistic group setting is associated with unintended improvements in depression and anxiety. Adults who used 5-MeO-DMT in a group setting with structured procedures 2019 Cross-sectional survey n = 362
The epidemiology of 5-methoxy- N, N-dimethyltryptamine (5-MeO-DMT) use: Benefits, consequences, patterns of use, subjective effects, and reasons for consumption. Adults who use 5-MeO-DMT, recruited via internet-based advertisements; predominantly... 2018 Cross-sectional survey n = 515
Dimethyltryptamine (DMT): Prevalence, user characteristics and abuse liability in a large global sample People who completed the Global Drug Survey online in 2012, many of whom have used drugs 2013 Cross-sectional survey n = 22,289

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