Locking away depression.
Jose Cesar Hernandez Silva, Christophe D Proulx
Science August 9, 2024 DOI: 10.1126/science.adq9566 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Peer reviewed |
|---|---|
| Intervention | Ketamine |
| Topics | Depression |
| Keywords | Mental health Ketamine therapy Depression treatment Psychopharmacology |
| Citations | 7 |
| Key points | Ketamine blocks neuroreceptors in hyperactive brain regions to produce its antidepressant effects. |
Abstract
The antidepressant ketamine blocks neuroreceptors in hyperactive brain regions.
Citations in the library
Cites 4
- NMDAR inhibition-independent antidepressant actions of ketamine metabolites Nature April 24, 2016
- Sustained antidepressant effect of ketamine through NMDAR trapping in the LHb Nature October 18, 2023
- Brain region-specific action of ketamine as a rapid antidepressant. Science August 9, 2024
- Sustained rescue of prefrontal circuit dysfunction by antidepressant-induced spine formation Science April 12, 2019