Skip to content

A Content Analysis of Social Media Discussions on THC-O-Acetate.

Daniel J. Kruger, Karahmet Amila, Sydney M Kaplan, John Redfield, Taylor Stacy, Vitush Agarwal, Mutaz Faqqouseh, Carlton Cb Bone

Cannabis 2023 DOI: 10.26828/cannabis/2023/000164 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Qualitative analysis Peer reviewed
Population Reddit users posting on the THCO subreddit
Topics Cannabis
Keywords = THC-O-Acetate Reddit Ketene Qualitative analysis Social media
Citations 15
Key findings The most common administration method for THC-O-acetate reported by users was heated inhalation, despite concerns about ketene gas release.

Abstract

Novel cannabinoids require systematic research to inform policies and practices. There is a growing interest in semi-synthetic cannabinoids by consumers, manufacturers, and regulators. However, there is a scarcity of research on these substances. Online discussion forums can provide guidance for research questions when current knowledge is scarce. The current project investigates the topics and issues covered in a social media forum devoted to THC-O-acetate (THCO), a semi-synthetic cannabinoid with rapidly rising popularity. Reddit comments posted on the THCO subreddit from June 2021 through November 2021 were coded for major and minor themes by a team of five coders and a supervisor. Major themes were established and clarified through group discussions. A second round of coding confirmed major themes and identified minor themes. The analysis identified several future research topics for THC-O-acetate, including the extent of variation in product composition, the characteristics of user experiences and comparisons with other substances, whether THC-O-acetate produces psychedelic effects, concerns and adverse experiences, and user harm reduction practices. As an acetate ester, THC-O-acetate may break down when heated and release toxic ketene gas. Although several users expressed safety concerns regarding THC-O-acetate, some explicitly mentioning ketene risk, the most common administration method reported was heated inhalation.

Comparable studies

Other qualitative studies on cannabis, most cited first.

Study Year Design Participants
Psychoactive substances as a last resort—a qualitative study of self-treatment of migraine and cluster headaches Users of online forums discussing cluster headache and migraine treatments 2017 Qualitative thematic analysis
Psychoactive drug or mystical incense? Overview of the online available information on Spice products Web pages related to Spice products 2009 Qualitative study n = 200
Patterns, Trends, and Meanings of Drug Use by Dance-drug Users in Edinburgh, Scotland Clubbers in clubs and pre-club bars 2004 Cross-sectional survey with focus groups n = 124
Fascination and Social Togetherness-Discussions about Spice Smoking on a Swedish Internet Forum. Swedish internet forum users who posted reports about Spice intoxication 2013 Qualitative study n = 40
Cannabis as entheogen: survey and interview data on the spiritual use of cannabis. Participants recruited from seven online communities, median age 33, 81% male 2020 Mixed methods (qualitative interviews and quantitative survey) n = 319

Citations in the library

Explore topics