Exploring the World of Psychedelics: An Introduction
August 30, 2024 DOI: 10.64239/pi-vl8201 (opens in new tab)
Summary
AI-generated from the abstractClassic psychedelics, including tryptamines like psilocybin and LSD and phenethylamines like MDMA and mescaline, have been used therapeutically for millennia across cultures and should not be called 'novel therapeutic agents.' Tryptamines are currently more studied. Most psychedelics are medically safe, but ibogaine and NBOMe compounds carry risks that need more discussion.
Study at a glance
| Characteristics | Review |
|---|---|
| Key finding | Psychedelics have a long history of therapeutic use and should not be considered novel; most are safe, but ibogaine and NBOMe compounds have associated risks. |
Abstract
Psychedelics have been used therapeutically for thousands of years by various cultures, and the term "novel therapeutic agent" should not describe them. The classic psychedelics are mainly tryptamines (e.g., psilocybin, DMT, LSD) and phenethylamines (e.g., MDMA, mescaline, 2C-B), with tryptamines being more studied currently. While most psychedelics are medically safe, some like ibogaine and NBOMe compounds have associated medical risks that require further discussion.