Updated Findings on the Efficacy of Combined Subanesthetic Ketamine Infusion and Cervical Sympathetic Blockade as a Symptomatic Treatment of PTSD/TBI in a Special Forces Patient with a 2-year Follow-up: A Case Report.
Eugene Lipov, Zubin Sethi, Hunter Rolain
Journal of special operations medicine : a peer reviewed journal for SOF medical professionals April 30, 2025 DOI: 10.55460/2QC5-PHPF (opens in new tab) via PubMed
Summary
AI-generated from the abstractA patient with PTSD and blast traumatic brain injury from a Special Operations Forces cohort received a combination treatment of cervical sympathetic blockade and ketamine infusion, called the SOF method. After being followed for 720 days, the treatment showed prolonged and sustained benefits for both PTSD and bTBI symptoms with further applications of the method.
Study at a glance
| Characteristics | Case report Peer reviewed |
|---|---|
| Sample size | 1 |
| Population | Special Operations Forces patient with PTSD and blast traumatic brain injury |
| Interventions | Cervical sympathetic blockade Ketamine infusion |
| Duration | 720 days |
| Topics | PTSD |
| Keywords | Sof Btbi Cervical sympathetic blockade Ketamine infusion Military-medicine |
| Key finding | The SOF method provided prolonged and sustained benefits for PTSD and bTBI symptoms over 720 days. |
Abstract
Posttraumatic stress disorder (PTSD)/blast traumatic brain injury (bTBI) in a Special Operations Forces (SOF) cohort has been shown to be successfully treated using a cervical sympathetic blockade (CSB)/ketamine infusion (KI) combination, termed the SOF method. In a prior case report, the patient was followed for 1 year. This report followed the same patient for a total of 720 days and found prolonged and sustained benefits with respect to PTSD and bTBI symptoms with further application of the SOF method.