Single ketamine infusion with behavioral therapy improves outcomes in cocaine‐dependent patients
The Brown University Psychopharmacology Update October 1, 2019 DOI: 10.1002/pu.30484 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Randomized controlled trial Peer reviewed |
|---|---|
| Sample size | 55 |
| Population | Individuals with cocaine dependence |
| Intervention | Ketamine |
| Dose | single infusion |
| Duration | 5-week trial |
| Topics | Esketamine Ketamine |
| Citations | 2 |
| Key findings | A single infusion of ketamine combined with mindfulness-based psychotherapy was more effective than midazolam with therapy in limiting craving and maintaining abstinence among individuals with cocaine dependence. |
Abstract
A five‐week trial involving 55 participants has concluded that a single infusion of ketamine in combination with a course of mindfulness‐based psychotherapy was more effective than midazolam with therapy in limiting craving and maintaining abstinence among individuals with cocaine dependence. The researchers found that participants receiving ketamine were 53% less likely to drop out of treatment or use cocaine in comparison with the midazolam group.