Adjunctive Ketamine With Relapse Prevention-Based Psychological Therapy in the Treatment of Alcohol Use Disorder
March 25, 2022 DOI: 10.64239/pi-qt3704 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Pilot trial Pilot study |
|---|---|
| Population | People with alcohol use disorder |
| Interventions | Ketamine mindfulness psychotherapy placebo alcohol psychoeducation |
| Topics | Addiction Esketamine Ketamine |
| Key findings | Ketamine plus mindfulness psychotherapy was more effective for sustained abstinence from alcohol than placebo plus alcohol psychoeducation. |
Abstract
Ketamine plus mindfulness psychotherapy was more effective for sustained abstinence from alcohol than placebo plus alcohol psychoeducation. Other combinations of these therapies were not significantly different from one another in this small pilot trial (N=20-25 in each group). Adverse effects were minimal, suggesting that current alcohol use is not a contraindication for consideration of ketamine.