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Beyond Enthusiasm: Ayahuasca and the Future of Depression Research.

Alberto Souza Sá Filho, James Oluwagbamigbe Fajemiroye, Antonio Egidio Nardi, Sérgio Machado

Revista Brasileira de Psiquiatria July 7, 2026 DOI: 10.47626/1516-4446-2026-5035 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Commentary Peer reviewed
Topics Ayahuasca Depression
Key points The author frames psychedelics as a potentially disruptive development in depression treatment, noting that many patients continue to experience partial response, relapse, or treatment resistance despite decades of prior work. The abstract is truncated and provides no specific results or conclusions.

Abstract

Few topics in contemporary psychiatry generate as much fascination, hope, and discomfort as the therapeutic use of psychedelics.For some, they represent a long-awaited disruption in the treatment of depression, a field in which many patients still experience partial response, relapse, or treatment resistance despite decades of

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  • Frames psychedelics as a potentially disruptive development in depression treatment, noting many patients still experience partial response, relapse, or treatment resistance.

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