Treatment of depressive and negative symptoms in individuals with schizoaffective disorders using serotoninergic psychedelics: a case report.
Michel Sabé, Federico Seragnoli, Gabriel Thorens, Daniele Zullino, Othman Sentissi, Marco Solmi, Kerem Böge, Stefan Kaiser, Matthias Kirschner
J Psychiatry Neurosci July 25, 2025 DOI: 10.1503/jpn.250005 (opens in new tab) via PubMed Central
Summary
AI-generated from the abstractA case report describes the use of serotoninergic psychedelics to treat depressive and negative symptoms in a person with schizoaffective disorder. The treatment was associated with improvements in these symptoms, suggesting a potential therapeutic benefit. The report highlights the need for further research into psychedelic-assisted therapy for this population.
Study at a glance
| Characteristics | Case report Peer reviewed |
|---|---|
| Sample size | 1 |
| Population | Individual with schizoaffective disorder |
| Dose | 25 mg |
| Duration | Two sessions, 6-month follow-up |
| Citations | 2 |
| Key finding | Serotoninergic psychedelics were associated with improvement in depressive and negative symptoms in a person with schizoaffective disorder. |
Abstract
Treatment of depressive and negative symptoms in individuals with schizoaffective disorders using serotoninergic psychedelics: a case report.