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[Intravenous Subnarcotic Ketamine Infusions for Treatment-Resistant Depression: Historical Development, Comparison with Esketamine Nasalspray, and Prospects].

Udo Bonnet, Norbert Scherbaum, Georg Juckel, Tom Bschor

Fortschr Neurol Psychiatr June 8, 2026 DOI: 10.1055/a-2846-4275 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Review Peer reviewed
Topics Depression Esketamine Ketamine
Key findings Intravenous subnarcotic ketamine infusions are effective for treatment-resistant depression, and comparison with esketamine nasal spray reveals differences in administration and potential efficacy.

Abstract

[Intravenous Subnarcotic Ketamine Infusions for Treatment-Resistant Depression: Historical Development, Comparison with Esketamine Nasalspray, and Prospects].