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Acute ketamine treatment produces long-term anxiolytic effects despite increasing oxidative stress in female Wistar Kyoto rats

Alena Lemeshova, Feysal Abdirahaman, Haney Haidari, Cherish Zhao, Aiman Limbada, Jennifer A. Honeycutt

bioRxiv July 1, 2026 preprint DOI: 10.64898/2026.06.26.734907 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Animal study
Population Female Wistar Kyoto rats
Intervention Ketamine
Topics Esketamine Ketamine
Key points Acute ketamine produces long-term anxiolytic effects in female Wistar Kyoto rats despite increasing oxidative stress.

Abstract

Acute ketamine treatment produces long-term anxiolytic effects despite increasing oxidative stress in female Wistar Kyoto rats