Skip to content

Transient or transformative? Psychedelics, agency and informed consent

Chiara Caporuscio

Journal of Medical Ethics March 10, 2026 DOI: 10.1136/jme-2025-111248 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Theoretical or philosophical paper Peer reviewed
Keywords Transformative learning Informed consent Agency philosophy Consciousness Power physics State computer science Altered state Sense of agency Process computing Beneficence Engineering ethics Law State agency Jungian analytical psychology
Key points Argues that the view that psychedelic experiences invalidate informed consent stems from a simplistic understanding of transformation, and that a two-step view—where lasting change requires a sober agential process after the experience—alleviates the pressure on informed consent.

Abstract

The literature on psychedelic experiences often highlights their transformative potential. This raises ethical questions about informed consent in psychedelic-assisted therapy: if the altered state of consciousness induced by psychedelic drugs can profoundly alter a person's value system in ways that are epistemically inaccessible to them beforehand, it is unclear whether their informed consent before the experience can be considered valid. I argue that this view stems from a simplistic understanding of psychedelic-mediated transformation, which overemphasises the power of the psychedelic experience in driving change. In most psychedelic-mediated changes, the experience of an altered state of consciousness is only the beginning of the transformative process: a lasting transformation requires patients to undertake a sober, authentic agential process following the psychedelic experience. I suggest that this two-step view of psychedelic transformation alleviates the pressure on informed consent.

Citations in the library

Explore topics