Endorsement of metaphysical idealism mediates a link between past use of psychedelics and wellbeing
Jussi Jylkkä, Andreas Krabbe, Patrick Jern
Scientific Reports June 10, 2024 DOI: 10.1038/s41598-024-63687-4 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Cross-sectional survey Peer reviewed |
|---|---|
| Sample size | 701 |
| Population | Participants with past experience of classical psychedelics |
| Keywords | Idealism Metaphysics Link geometry Epistemology |
| Citations | 11 |
| Key findings | Idealism, but not non-physicalist beliefs generally or Materialism, mediated a link between past psychedelic use and wellbeing. |
Abstract
It has been proposed that psychedelics promote wellbeing through spiritual-type transformations, involving changes in metaphysical beliefs. Past empirical research shows a link between the use of psychedelics and the endorsement of non-physicalist metaphysical beliefs. However, non-physicalist beliefs encompass a wide range of metaphysical ideas, and their links to wellbeing and psychedelics use remain unclear. We utilized a cross-sectional Internet survey to probe the metaphysical beliefs of participants (N = 701) with past experience of classical psychedelics, using a novel 42-item questionnaire (Core Metaphysical Beliefs, CMB), encompassing a wide range of metaphysical beliefs. Factor analysis of CMB revealed two factors, Idealism and Materialism. In network analyses, Idealism was linked to psychological insight in a past psychedelic experience (E = 0.24) and average use of psychedelics (E = 0.16), and predicted wellbeing (Es = 0.13 and 0.22). Mediation analyses showed an indirect link from past psychedelics use through Idealism to wellbeing (ps ≤ .005). Non-Physicalist Beliefs or Materialism were not significant mediators. The results indicate that Idealism specifically, not non-physicalist beliefs generally, mediate a link between the use of psychedelics and wellbeing. Future research is required to establish whether the link is causal, and to understand what the Idealism factor means.
Citations in the library
Cited by 10
- Insights on psychedelics: A systematic review of therapeutic effects. Neuroscience & Biobehavioral Reviews June 1, 2025
- Acceptance as a possible link between past psychedelic experiences and psychological flexibility. Scientific Reports October 16, 2024
- Neurocognitive effects of psilocybin: A systematic and comprehensive review of neuroimaging studies in humans. Neuroscience & Biobehavioral Reviews August 1, 2025
- Therapeutic benefit versus epistemic risk: Need for empirical research in psychedelic epistemology. Journal of Psychiatric Research August 1, 2025
- Meditation and psychedelics facilitate similar types of mystical, psychological, and philosophical-existential insights predictive of wellbeing: a qualitative-quantitative approach. Consciousness and Cognition July 7, 2025
and 5 more in the library
Cites 24
- Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer: A randomized double-blind trial Journal of Psychopharmacology November 30, 2016
- Psilocybin can occasion mystical-type experiences having substantial and sustained personal meaning and spiritual significance Psychopharmacology July 7, 2006
- Effects of Psilocybin-Assisted Therapy on Major Depressive Disorder JAMA Psychiatry November 4, 2020
- REBUS and the Anarchic Brain: Toward a Unified Model of the Brain Action of Psychedelics Pharmacological Reviews June 20, 2019
- Psilocybin occasioned mystical-type experiences: immediate and persisting dose-related effects. Psychopharmacology December 1, 2011
and 19 more in the library