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Reshaping human neurons.

Jessica L Maltman, Javier González-Maeso

Elife March 31, 2026 DOI: 10.7554/elife.110981 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Experimental study Peer reviewed
Population Human induced pluripotent stem cell derived cortical neurons
Intervention Psilocin
Topics Neuroplasticity Psilocybin Serotonin
Keywords Bdnf Human Psychedelics
Key findings Psilocin increases structural complexity and strengthens synaptic connections in human induced pluripotent stem cell derived cortical neurons.

Abstract

Human neurons derived from stem cells show increased structural complexity and stronger synaptic connections after exposure to psilocin, the active metabolite of the psychedelic psilocybin.

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