Psychedelics beyond medicine: Treatment, enhancement, hype, consent, and the limits of medicalization
Mina Caraccio, Katherine Cheung, Sebastian Porsdam Mann, Lori Bruce, Edward Jacobs, Daniel Villiger, Julian D. Sandbrink, Christopher Register, Ivar R. Hannikainen, Mette Leonard Høeg, Sean K Clancy, Khaleel Rajwani, Emma C. Gordon, Giovanni Spitale, Neil Levy, Keisha S. Ray, Yuria Celidwen, Ilina Singh, Julian Savulescu, David B. Yaden, Brian D. Earp
Philosophical Psychology September 8, 2025 DOI: 10.1080/09515089.2025.2532761 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Theoretical or philosophical paper Peer reviewed |
|---|---|
| Keywords | Exceptionalism Medicalization Accountability Interpretation philosophy Bioethics Transhumanism Ethical issues Epistemology Engineering ethics Flexibility engineering Neuroethics Consciousness Diversity politics |
| Citations | 3 |
| Key points | Argues that ethical guidelines for psychedelics must address non-medical applications and the treatment-versus-enhancement distinction, and that neglecting these may affect issues like hype, exceptionalism, consent, and access. |
Abstract
The current revival of interest in classic psychedelics and other psychoactives such as ketamine and MDMA, coupled with changes to their regulatory status in many jurisdictions, necessitates rigorous ethical guidelines both within and beyond clinical and scientific contexts. This paper examines crucial ethical, philosophical, and policy considerations needed to ensure psychedelic use across various settings remains equitable, beneficial, consensual, and safe, with appropriate accountability mechanisms for addressing potential harms. We seek to broaden the lens beyond the medical model of psychedelics to include potentially valuable non-medical applications that could benefit individuals, communities, and society. With popular interest in psychedelics growing outside of therapeutic and research settings, there is a need to determine which aspects of any proffered guidelines, or underlying principles, should be applied similarly across contexts and in what ways there should be flexibility and/or context-sensitivity in their interpretation or application. In developing such guidelines, we suggest the “treatment versus enhancement” distinction – and associated debates familiar from bioethics and philosophy of medicine – requires renewed attention. We argue that neglecting non-medical and broad scientific use cases for psychedelics may have important implications for a range of ethical issues surrounding psychedelic use and research, including concerns about psychedelic hype and exceptionalism (both positive and negative), therapeutic touch, informed consent, data-gathering, and balancing access and safety. We conclude with suggestions for future directions in research and policy in the burgeoning area of psychedelic bioethics, stressing the importance of incorporating the perspectives of a diversity of stakeholders and fostering cross-sector collaboration.
Citations in the library
Cited by 4
- Exploring critical psychedelic phenomenology: What Frantz Fanon can teach us about psychedelic therapy for racialized and colonized people Psychedelics August 15, 2026
- T-shaped expertise: rethinking interdisciplinarity in psychedelic research Psychedelics June 28, 2026
- Trials, trips, and tribulations: pathways for implementing psychedelic therapy in Ireland. The International Journal of Neuropsychopharmacology June 2, 2026
- Ethics of psychedelics in clinical research: a state-of-the-field review JME Practical Bioethics October 9, 2026
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