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Editorial: Old and new psychoactive substances: Pharmacology and potential applications

Felix P. Mayer, Dino Luethi, Lorena B. Areal, Harald H. Sitte

Frontiers in Psychiatry January 4, 2023 DOI: 10.3389/fpsyt.2022.1087005 (opens in new tab)

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AI-extracted from the abstract
Characteristics Historical analysis Peer reviewed
Keywords Psychopharmacology
Citations 1
Key points Argues that psychoactive substance consumption is inextricably linked with human history, with longstanding evidence for plant- and fungus-derived substances such as cathinone from Catha edulis and muscimol from Amanita muscaria, and for alcoholic beverages. Contends that refined chemical approaches later added isolated compounds such as cocaine and synthetic compounds such as N-methylamphetamine and LSD to the repertoire of psychoactive drugs.

Abstract

The consumption of psychoactive substances is inextricably linked with human history. Longstanding evidence supports the consumption of psychoactive substances that are found in plants and fungi (e.g. cathinone and muscimol, which are present in Catha edulis and Amanita muscaria, respectively) and alcoholic beverages. With the advent of more refined chemical approaches, isolated (e.g. cocaine) and purely synthetic (e.g. N-methylamphetamine and lysergic acid diethylamide (LSD)) compounds were added to the repertoire of drugs with psychoactive properties.

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