Moral Considerations and the Experience of Ego Dissolution: Insights from Psilocybin
Azimjon Karimov, Dilshodbek Rasulov
Asian Journal of Ethics in Health and Medicine 2025 DOI: 10.51847/ml10ckoxsw (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Review Peer reviewed |
|---|---|
| Topics | Ego dissolution Psilocybin |
| Citations | 1 |
| Key findings | Early-phase studies indicate psychedelics may offer unique therapeutic benefits for mental health and substance use disorders, involving phenomena such as diminished self-importance and feelings of unity. |
Abstract
Although psychedelics were banned from medical research for about fifty years, recent early-phase studies indicate they may offer unique therapeutic benefits for various mental health and substance use disorders. When effective, psychedelic experiences often involve phenomena not typically observed in other medical or psychiatric interventions, such as a diminished sense of self-importance, insights that are difficult to articulate, feelings of connection and unity with others, and encounters wi
Comparable studies
Other narrative reviews on ego dissolution, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| Neural Mechanisms and Psychology of Psychedelic Ego Dissolution | 2022 | Review | |
| A narrative synthesis of research with 5-MeO-DMT. | 2022 | Review | |
| Scoping Review of Experiential Measures from Psychedelic Research and Clinical Trials. | 2023 | Review | |
| Psychedelics and connectedness to natural and social worlds: An examination of the evidence and a proposed conceptual framework. | 2025 | Review | |
| Singularity and consciousness: A neuropsychological contribution. Split-brain patient | 2021 | Review | n = 1 |
Citations in the library
Cites 35
- Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer: A randomized double-blind trial Journal of Psychopharmacology November 30, 2016
- Rapid and sustained symptom reduction following psilocybin treatment for anxiety and depression in patients with life-threatening cancer: a randomized controlled trial Journal of Psychopharmacology November 30, 2016
- Psilocybin with psychological support for treatment-resistant depression: an open-label feasibility study. The Lancet Psychiatry May 17, 2016
- The entropic brain: a theory of conscious states informed by neuroimaging research with psychedelic drugs Frontiers in Human Neuroscience 2014
- Neural correlates of the psychedelic state as determined by fMRI studies with psilocybin Proceedings of the National Academy of Sciences January 23, 2012
and 30 more in the library