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Deaths following illicit ketamine use in England, Wales and Northern Ireland 1999–2024: An update report to inform the reclassification debate

Jade Pullen, John Corkery, Rebecca Mcknight, Caroline S Copeland

Journal of Psychopharmacology September 29, 2025 DOI: 10.1177/02698811251373058 (opens in new tab)

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AI-extracted from the abstract
Characteristics Review Peer reviewed
Topics Ketamine Esketamine
Keywords Northern ireland Harm Legislature Legislation Medical emergency Criminology Medline Injury prevention Suicide prevention Poison control
Citations 3
Key findings Deaths following illicit ketamine use have accelerated, with increasing complexity of polydrug use and socio-economic vulnerability, requiring policy responses beyond single-substance legislative controls.

Abstract

There has been an acceleration in deaths following illicit ketamine in recent years, which are increasingly featuring complex patterns of polydrug use and socio-economic vulnerability. Policy responses must extend beyond single-substance legislative controls to encompass harm reduction, treatment integration, and social support strategies.

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