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Angel Dust

Sidney Cohen

JAMA August 8, 1977 DOI: 10.1001/jama.1977.03280060059027 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Historical analysis Peer reviewed
Topics Ketamine Mescaline
Keywords Phencyclidine Ketamine hydrochloride Anesthetic agent Anesthesia Pharmacology
Citations 31
Key points Describes the history and street availability of phencyclidine, noting that its manufacture from readily available precursors explains its common use as a substitute for other psychedelic drugs.

Abstract

PHENCYCLIDINE hydrochloride (Sernylan) was investigated during the 1950s as an anesthetic agent. Although it was found to be effective for analgesia and anesthesia, certain side effects, especially postoperative agitation and delirium that lasts for hours, precluded its final acceptance. Later, phencyclidine was discovered to be a satisfactory anesthetic agent for certain animals, and is currently marketed for that purpose. A chemically related compound, ketamine hydrochloride (Ketalar) is employed as a human anesthetic. On the street, phencyclidine is known by some 20 names, including "Angel Dust," "PCP," and "Hog." Angel dust appears in many forms: as a crystalline powder, and as tablets and capsules in a variety of colors, shapes, and sizes. Angel dust is manufactured by kitchen chemists from readily available precursors. The procedure is not complicated and supplies are plentiful. This explains why phencyclidine is a common substitute for less available psychedelic drugs such as mescaline. An occasional batch

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