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A Possible Case of Venlafaxine-Induced Stevens-Johnson Syndrome

Nicholas Weiss, Lee Jones, John Chamberlain

The Journal of Clinical Psychiatry October 15, 2004 DOI: 10.4088/jcp.v65n1020d (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Case study Case report Peer reviewed
Sample size 1
Population A person who used peyote
Intervention sleep initiation
Topics Mescaline
Keywords Hallucinogen Psychosis Sleep deprivation Sleep system call Drug-induced adverse reactions Chemotherapy-related skin toxicity
Citations 33
Key findings Prolonged peyote-triggered psychosis and sleep deprivation were resolved by sleep initiation.

Abstract

Article AbstractBecause this piece does not have an abstract, we have provided for your benefit the first 3 sentences of the full text.Sir: Psychosis due to sleep deprivation has been frequently reported.1 In hallucinogen use, however, the duration of sleep deprivation is usually limited to a few days, and psychosis is attributed to the direct effects of the hallucinogens on the central nervous system. As a source of hallucinogen, the peyote cactus has been used both as a psychedelic drug and, among many Native Americans in the southwestern United States and Mexico, as a spiritual sacrament. The active ingredient is believed to be mescaline, an alkaloid known to cause visual hallucinations and decreased sleep. These effects subside in a few days, with an average duration of 10 to 12 hours.2 Here, we report a case of prolonged peyote-triggered psychosis and sleep deprivation that was resolved by sleep initiation.

Comparable studies

Other case reports and case series on mescaline, most cited first.

Study Year Design Participants
Parkinsonism after Taking Ecstasy 29-year-old man 1999 Case study n = 1
Methylenedioxyamphetamine. Clinical description of overdose, death, and review of pharmacology A patient with methylenedioxyamphetamine intoxication 1981 Case study n = 1
A New Hallucinogen: 3,4,5-Trimethoxyphenyl-β-Aminopropane 1955 Case study
Peyote and mescaline exposures: a 12-year review of a statewide poison center database Patients who used peyote or mescaline and required treatment 2010 Case series
A Mescaline Associated Fatality A single deceased individual under the influence of mescaline 1985 Case study n = 1

Citations in the library

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