Methylenedioxyamphetamine
Archives of Internal Medicine October 1, 1981 DOI: 10.1001/archinte.1981.00340120115023 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Case study Case report Peer reviewed |
|---|---|
| Sample size | 1 |
| Population | A patient with methylenedioxyamphetamine toxicity |
| Keywords | Hyperthermia Coma optics Drug Phentolamine Anesthesia Pharmacology Propranolol Plant-based medicinal research |
| Citations | 36 |
| Key findings | Methylenedioxyamphetamine can cause fatal hyperthermia and other severe symptoms, and phentolamine mesylate may be the preferred treatment for hyperthermia in such cases. |
Abstract
Methylenedioxyamphetamine is a commonly used "street drug," with a reputation of providing a "good trip." The drug is structurally similar to both mescaline and amphetamine. The following symptoms were found in a patient: sympathomimetic effects, coma, seizures, hyperreflexia, and hyperthermia. The patient's condition was initially stabilized and then deteriorated with uncontrollable hyperthermia, hematologic abnormalities, and coma that culminated in death. Since the hyperthermia is based on both central and peripheral mechanisms, phentolamine (Regitine) mesylate may be the preferred drug to be used in the treatment of future cases. The concept that this drug is primarily a hallucinogen with mild toxicity is erroneous. (Arch Intern Med1981;141:1507-1509)
Citations in the library
Cited by 11
- Hallucinogenic Amphetamine Selectively Destroys Brain Serotonin Nerve Terminals Science September 6, 1985
- Ecstasy (MDMA) Deaths in New York City: A Case Series and Review of the Literature Journal of Forensic Sciences 2002
- ECSTACY: A Review of MDMA and MDA The International Journal of Psychiatry in Medicine December 1, 1987
- Use of MDA (The "Love Drug") and Methamphetamine in Toronto by Unsuspecting Users of Ecstasy (MDMA) Journal of Forensic Sciences September 1, 2004
- Isolated non-cardiogenic pulmonary edema - A rare complication of MDMA toxicity. The American Journal of Emergency Medicine September 2017
and 6 more in the library