ECSTACY: A Review of MDMA and MDA
Robert P. Climko, Herbert Roehrich, Donald R. Sweeney, Jamil Al-Razi
The International Journal of Psychiatry in Medicine December 1, 1987 DOI: 10.2190/dcrp-u22m-aumd-d84h (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Review Peer reviewed |
|---|---|
| Topics | MDMA |
| Keywords | Amphetamine Drug Pharmacology |
| Citations | 77 |
| Key findings | The classification of MDMA as a Schedule I substance remains controversial due to questions about its efficacy as a psychotherapy adjunct and the regulation of designer drugs. |
Abstract
The Drug Enforcement Administration classified the drug methylenedioxymeth-amphetamine, MDMA, also known as Ecstacy, as a Schedule I controlled substance on July 1, 1985. The controversy surrounding the classification of MDMA is related to the question of its efficacy as an adjunct to psychotherapy and the larger issue of how to regulate the production and use of designer drugs. The authors review the literature on MDMA and its predecessor, MDA, a substance that differs from MDMA by one methyl group.
Comparable studies
Other narrative reviews on MDMA, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| Human Pharmacology of MDMA | 2004 | Review | |
| Human psychopharmacology of Ecstasy (MDMA): a review of 15 years of empirical research | 2001 | Review | |
| 3,4‐Methylenedioxymethamphetamine (MDMA, “Ecstasy”): pharmacology and toxicology in animals and humans | 1994 | Review | |
| (±)3,4-Methylenedioxymethamphetamine (‘Ecstasy’)-Induced Serotonin Neurotoxicity: Studies in Animals | 2000 | Review | |
| Amphetamine toxicities | 2010 | Review |
Citations in the library
Cited by 32
- Recreational MDMA use in Sydney: a profile of ‘Ecstasy’ users and their experiences with the drug British Journal of Addiction August 1, 1992
- The origin of MDMA (ecstasy) revisited: the true story reconstructed from the original documents* Addiction July 8, 2006
- Stereospecific Analysis and Enantiomeric Disposition of 3,4-Methylenedioxymethamphetamine (Ecstasy) in Humans Clinical Chemistry July 1, 1999
- Dark Classics in Chemical Neuroscience: 3,4-Methylenedioxymethamphetamine ACS Chemical Neuroscience July 12, 2018
- An Exploration of the History and Controversies Surrounding MDMA and MDA Journal of Psychoactive Drugs September 1, 2001
and 27 more in the library
Cites 15
- Hallucinogenic Amphetamine Selectively Destroys Brain Serotonin Nerve Terminals Science September 6, 1985
- Effects of certain hallucinogenic amphetamine analogs on the release of [3H]-serotonin from rat brain synaptosomes Journal of Medicinal Chemistry May 1, 1982
- Methylenedioxyamphetamine (MDA)–Subjective Effects Journal of Psychedelic Drugs 1974
- Methylenedioxyamphetamine. Clinical description of overdose, death, and review of pharmacology Archives of Internal Medicine October 1, 1981
- MDA-ASSISTED PSYCHOTHERAPY WITH NEUROTIC OUTPATIENTS The Journal of Nervous and Mental Disease October 1, 1976
and 10 more in the library