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Navajo Peyote Use: Its Apparent Safety

Robert G. Bergman

American Journal of Psychiatry December 1, 1971 DOI: 10.1176/ajp.128.6.695 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Observational study Peer reviewed
Population Members of an American Indian religion that uses peyote
Intervention peyote
Topics Mescaline
Keywords Navajo Feeling Hallucinogen Population Traditional medicine
Citations 70
Key findings The rate of serious emotional disturbance among members of this religion was very low, likely due to cultural and religious practices that channel the drug experience positively.

Abstract

An American Indian religion uses significant quantities of peyote, a hallucinogenic plant containing mescaline. Since there have been many reports of serious emotional disturbance caused by similar drugs, the rate of such illness in this population was investigated. The rate was found to be very low, probably because the feelings evoked by the drug experience are channeled by church belief and practice into ego-strengthening directions and there are built-in safeguards against bad reactions.

Comparable studies

Other observational and cohort studies on mescaline, most cited first.

Study Year Design Participants
Psychedelics not linked to mental health problems or suicidal behavior: A population study Randomly selected United States adults 2015 Observational cohort n = 135,095
Long-lasting subjective effects of LSD in normal subjects Healthy participants 2017 Observational cohort n = 16
Psychological and cognitive effects of long-term peyote use among Native Americans. Navajo Native Americans aged 18-45 2005 Observational cohort n = 176
Mescaline-induced psychopathological, neuropsychological, and neurometabolic effects in normal subjects: experimental psychosis as a tool for psychiatric research. Normal men who were volunteers 1992 Observational cohort n = 12
2,5-Dimethoxy-4-methyl-amphetamine (STP): A New Hallucinogenic Drug Normal control volunteers 1967 Observational study

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