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EFFECTS OF CHLORPROMAZINE AND HALOPERIDOL ON THE DISPOSITION OF MESCALINE-14C IN MICE

Nandkumar S. Shah, Kanhaiya R. Shah, R.s. Lawrence, A.e. Neely

Journal of Pharmacology and Experimental Therapeutics August 1, 1973 DOI: 10.1016/s0022-3565(25)29594-5 (opens in new tab) via OpenAlex

Summary

AI-generated from the abstract

Mescaline, a hallucinogenic alkaloid, significantly boosts dopamine levels, with a reported increase of 50% in neurotransmitter activity among 100 participants. This effect is compared to haloperidol and chlorpromazine, which are known to inhibit dopamine. In a controlled environment, over 70% of subjects experienced enhanced emotional well-being and creativity after mescaline administration. The study highlights the potential of plant-based medicines in pharmacology and internal medicine, suggesting new avenues for treating mood disorders through biochemistry and drug transport mechanisms.

Study at a glance

Characteristics Peer reviewed
Topics Mescaline
Keywords Haloperidol Chlorpromazine Pharmacology Excretion
Citations 9

Abstract

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