Phenomenology and Sequelae of 3,4-Methylenedioxymethamphetamine Use
Mitchell B. Liester, Charles S. Grob, Gary Bravo, Roger Walsh
The Journal of Nervous and Mental Disease June 1, 1992 DOI: 10.1097/00005053-199206000-00001 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Qualitative study Peer reviewed |
|---|---|
| Sample size | 20 |
| Population | Psychiatrists who had taken MDMA |
| Intervention | MDMA |
| Topics | MDMA Philosophy of mind |
| Keywords | Pleasure Psychotherapist Clinical psychology |
| Citations | 130 |
| Key findings | The study provides retrospective self-report data on the subjective experience of MDMA and its psychological and behavioral sequelae, including side effects, insight, pleasure, and the influence of set, setting, and dosage. |
Abstract
3,4-Methylenedioxymethamphetamine (MDMA) has been at the center of a debate over its potential benefits as an adjunct to psychotherapy versus its capability for neurotoxic effects and is currently classified as a Schedule 1 drug by the Drug Enforcement Administration (DEA). However, as yet, there is very little methodological data on the subjective experience of the MDMA-induced state or its psychological and behavioral sequelae. The present study was, therefore, designed to obtain this kind of information. Twenty psychiatrists who had taken MDMA previously were evaluated using a semistructured interview. Subjective experience of the actual MDMA-induced state, as well as both short-term (less than 1 week) and relatively longer term (greater than 1 week) sequelae, were examined retrospectively. Side effects, insight gained, pleasure, and intensity of the MDMA experience were evaluated as were the influence of set and setting at the time the MDMA was taken and the dosage utilized. Finally, the authors discuss methodological problems and limitations of a study of this type.
Comparable studies
Other qualitative studies on MDMA, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| MDMA and Sexual Behavior: Ecstasy Users' Perceptions About Sexuality and Sexual Risk Current and former users of MDMA | 2005 | Qualitative study | n = 98 |
| Perceived Benefits of MDMA-Assisted Psychotherapy beyond Symptom Reduction: Qualitative Follow-Up Study of a Clinical Trial for Individuals with Treatment-Resistant PTSD Veterans, firefighters, and police officers with chronic, treatment-resistant PTSD | 2019 | Qualitative study using interpretative phenomenological analysis | n = 19 |
| Negative Experiences on Ecstasy: The Role of Drug, Set, and Setting Current or former users of Ecstasy | 2002 | Qualitative study | n = 98 |
| A Qualitative Exploration of Relational Ethical Challenges and Practices in Psychedelic Healing Practitioners who have administered MDMA and psilocybin to clients in underground... | 2021 | Qualitative study | n = 23 |
| Patterns, Trends, and Meanings of Drug Use by Dance-drug Users in Edinburgh, Scotland Clubbers in clubs and pre-club bars | 2004 | Cross-sectional survey with focus groups | n = 124 |
Citations in the library
Cited by 49
- 3,4‐Methylenedioxymethamphetamine (MDMA, “Ecstasy”): pharmacology and toxicology in animals and humans Addiction May 1, 1994
- Mood and cognitive effects of ± 3,4‐methylenedioxymethamphetamine (MDMA, ‘ecstasy’): week‐end ‘high’ followed by mid‐week low Addiction July 1, 1997
- Human Pharmacology of 3,4-Methylenedioxymeth-amphetamine ("Ecstasy"): Psychomotor Performance and Subjective Effects Journal of Clinical Psychopharmacology August 1, 2000
- Cognitive performance in recreational users of MDMA or 'ecstasy': evidence for memory deficits Journal of Psychopharmacology 1998
- Developing Guidelines and Competencies for the Training of Psychedelic Therapists Journal of Humanistic Psychology June 29, 2017
and 44 more in the library