Hallucinogen Use Disorders Among Adult Users of MDMA and Other Hallucinogens
Li-Tzy Wu, Christopher L. Ringwalt, Paolo Mannelli, Ashwin A. Patkar
American Journal on Addictions September 3, 2008 DOI: 10.1080/10550490802269064 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Observational cohort Peer reviewed |
|---|---|
| Sample size | 37,227 |
| Population | American adults aged 18 or older who used MDMA or other hallucinogens in the past year |
| Topics | Cannabis MDMA |
| Keywords | Hallucinogen |
| Citations | 30 |
| Key findings | One in five past-year MDMA users and one in six other hallucinogen users reported at least one clinical feature of hallucinogen use disorders, with subthreshold dependence being relatively prevalent. |
Abstract
We investigated the prevalence, patterns, and correlates of past‐year DSM‐IV hallucinogen use disorders (HUDs) among past‐year users of MDMA and other hallucinogens from a sample of Americans 18 or older (n = 37,227). Users were categorized as MDMA users and other hallucinogen users. Overall, one in five (20%) MDMA users and about one in six (16%) other hallucinogen users reported at least one clinical feature of HUDs. Among MDMA users, prevalence of hallucinogen abuse, subthreshold dependence, and dependence was 4.9%, 11.9%, and 3.6%, respectively. The majority with hallucinogen abuse displayed subthreshold dependence. Most with hallucinogen dependence exhibited abuse. Subthreshold hallucinogen dependence is relatively prevalent and represents a clinically important subgroup that warrants future research and consideration in a major diagnostic classification system.
Comparable studies
Other observational and cohort studies on MDMA, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| Subjective Reports of the Effects of MDMA in a Clinical Setting Individuals who took MDMA in a clinical setting | 1986 | Observational study | |
| Memory impairment in abstinent MDMA ("Ecstasy") users Abstinent MDMA users | 1998 | Observational cohort | |
| Impaired cognitive performance in drug free users of recreational ecstasy (MDMA) Otherwise healthy young people | 2000 | Observational | |
| The Psychological and Physiological Effects of MDMA on Normal Volunteers Older, more educated, drug-experienced individuals | 1986 | Observational cohort | |
| Cognitive performance in recreational users of MDMA or 'ecstasy': evidence for memory deficits Young people who were regular or novice MDMA users, or non-users | 1998 | Observational cohort | n = 30 |
Citations in the library
Cited by 14
- The epidemiology of 5-methoxy- N, N-dimethyltryptamine (5-MeO-DMT) use: Benefits, consequences, patterns of use, subjective effects, and reasons for consumption. Journal of Psychopharmacology July 1, 2018
- Emerging psychoactive substance use among regular ecstasy users in Australia. Drug and Alcohol Dependence July 1, 2012
- Self-reported prevalence of dependence of MDMA compared to cocaine, mephedrone and ketamine among a sample of recreational poly-drug users International Journal of Drug Policy July 15, 2014
- Recent national trends in Salvia divinorum use and substance-use disorders among recent and former Salvia divinorum users compared with nonusers. Substance Abuse and Rehabilitation April 1, 2011
- From taboo to treatment: The emergence of psychedelics in the management of pain and opioid use disorder. British Journal of Clinical Pharmacology December 1, 2024
and 9 more in the library
Cites 11
- Human psychopharmacology of Ecstasy (MDMA): a review of 15 years of empirical research Human Psychopharmacology: Clinical and Experimental December 1, 2001
- Ecstasy (MDMA) dependence Drug and Alcohol Dependence January 7, 1999
- Long-Term Neuropsychiatric Consequences of "Ecstasy" (MDMA): A Review Harvard Review of Psychiatry 2002
- Is the Use of Ecstasy and Hallucinogens Increasing? European Addiction Research 1998
- Death rates from ecstasy (MDMA, MDA) and polydrug use in England and Wales 1996–2002 Human Psychopharmacology: Clinical and Experimental September 19, 2003
and 6 more in the library