Ecstasy (MDMA) dependence
Drug and Alcohol Dependence January 7, 1999 DOI: 10.1016/s0376-8716(98)00111-2 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Case series Case report Peer reviewed |
|---|---|
| Sample size | 3 |
| Population | Individuals meeting criteria for MDMA dependence |
| Topics | Addiction MDMA |
| Keywords | Cocaine dependence |
| Citations | 127 |
| Key findings | MDMA can meet criteria for dependence in rare cases, and very heavy use may cause lasting neuronal changes. |
Abstract
Methylenedioxymethamphetamine (MDMA) is generally described as non-addictive. However, this report describes three cases in which criteria for dependence were met. A wider understanding that MDMA can be addictive in rare cases is important as very heavy use may cause lasting neuronal changes. This risk could be reduced with effective identification and treatment of dependent persons. In one case dependence was linked with self-medication of post-traumatic stress disorder (PTSD).