Verbal Memory Deficits Are Correlated with Prefrontal Hypometabolism in 18FDG PET of Recreational MDMA Users
Oliver G. Bosch, Michael Wagner, Frank Jessen, Kai‐uwe Kühn, Alexius Joe, Erich Seifritz, Wolfgang Maier, Hans‐jürgen Biersack, Boris B. Quednow
PLoS One April 9, 2013 DOI: 10.1371/journal.pone.0061234 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Correlational study Peer reviewed |
|---|---|
| Population | Recreational MDMA users |
| Topics | MDMA |
| Keywords | Hippocampus Dorsolateral prefrontal cortex Verbal memory Audiology |
| Citations | 34 |
| Key points | Verbal learning and recall deficits in MDMA users are correlated with glucose hypometabolism in prefrontal and parietal cortex, and word recognition deficits are additionally correlated with mediotemporal hypometabolism. |
Abstract
Verbal learning and recall deficits of recreational MDMA users are correlated with glucose hypometabolism in prefrontal and parietal cortex, while word recognition was additionally correlated with mediotemporal hypometabolism. We conclude that memory deficits of MDMA users arise from combined fronto-parieto-mediotemporal dysfunction.