MDMA induced hyperthermia: a survivor with an initial body temperature of 42.9 degrees C.
Emergency Medicine Journal September 1, 1997 DOI: 10.1136/emj.14.5.336 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Case study Case report Peer reviewed |
|---|---|
| Sample size | 1 |
| Population | Young male who ingested MDMA |
| Interventions | assisted ventilation aggressive fluid therapy dantrolene cooling measures |
| Topics | MDMA |
| Keywords | Rhabdomyolysis Dantrolene Anesthesia Ingestion Metabolic acidosis Malignant hyperthermia Restraint-related deaths |
| Citations | 59 |
| Key findings | A young male survived severe hyperpyrexia (42.9 °C) after MDMA ingestion with treatment including dantrolene, aggressive fluids, and assisted ventilation. |
Abstract
A young male survived hyperpyrexia (42.9 degrees C) following MDMA ("Ecstasy") ingestion. He developed convulsions, rhabdomyolysis, metabolic acidosis, and respiratory failure. This was successfully managed by assisted ventilation, aggressive fluid therapy, and the early administration of dantrolene, in addition to cooling measures. This is the first report of a survivor with such a severe hyperpyrexia.