Virada maníaca induzida por Ayahuasca em um homem com transtorno bipolar: relato de caso com revisão de literatura
André Botelho Oliveira, Babington Rodrigo Silva, Eduardo Trachtenberg, Adonay Genovese Filho, José Ricardo de Pinto Abreu
Debates em Psiquiatria May 31, 2018 DOI: 10.25118/2763-9037.2018.v8.326 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Case study Case report Peer reviewed |
|---|---|
| Sample size | 1 |
| Population | 30-year-old man with bipolar type 1 disorder |
| Intervention | Ayahuasca |
| Topics | Ayahuasca |
| Citations | 1 |
| Key findings | Ayahuasca consumption triggered a manic switch in a mixed episode and increased suicidal ideation in a patient with bipolar type 1 disorder. |
Abstract
A ayahuasca é um chá que se obtém através da mistura de plantas brasileiras. Já existem várias hipóteses que corroboram suas ações antidepressivas pela inibição da enzima monoamina oxidase (MAO) e de virada maníaca com o seu uso. Este artigo descreve o caso de um homem de 30 anos de idade com diagnóstico de transtorno bipolar tipo 1 (TB tipo 1) prévio, que apresentou, após o consumo do chá, virada maníaca em um episódio misto, com remissão do quadro após abstinência e terapêutica estabilizadora de humor. A literatura ainda é escassa, e são poucos os relatos de caso publicados até o momento. Além da virada maníaca, o caso destaca o aumento de ideação e comportamento suicida com o uso do chá nessa população e corrobora a hipótese antidepressiva da ayahuasca a partir da virada maníaca em um paciente TB tipo 1 prévio.
Comparable studies
Other case reports and case series on ayahuasca, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| A fatal intoxication following the ingestion of 5-methoxy-N,N-dimethyltryptamine in an ayahuasca preparation. 25-year-old white male | 2005 | Case study | n = 1 |
| The Diaspora of Brazilian Religions | 2013 | Ethnographic case studies | |
| EEG Gamma Coherence and Other Correlates of Subjective Reports During Ayahuasca Experiences Experienced ayahuasca users | 2005 | Exploratory case series | n = 2 |
| Reply to “Ayahuasca turned on my mind’s eye”: A case of acquired versus congenital aphantasia, as evidenced with DMT use? Individual with apparent congenital aphantasia | 2018 | Case study | n = 1 |
| “Ayahuasca turned on my mind’s eye”: Enhanced visual imagery after ayahuasca intake in a man with “blind imagination” (aphantasia) A man self-diagnosed with long-lasting aphantasia | 2018 | Case study | n = 1 |
Citations in the library
Cites 5
- Efficacy, tolerability, and safety of serotonergic psychedelics for the management of mood, anxiety, and substance-use disorders: a systematic review of systematic reviews Expert Review of Clinical Pharmacology August 13, 2018
- Ayahuasca: Pharmacology, neuroscience and therapeutic potential Brain Research Bulletin March 11, 2016
- Antidepressive and anxiolytic effects of ayahuasca: a systematic literature review of animal and human studies Brazilian Journal of Psychiatry March 1, 2016
- Ayahuasca: An ancient sacrament for treatment of contemporary psychiatric illness? Mental Health Clinician 2017
- Ayahuasca: what mental health professionals need to know Archives of Clinical Psychiatry (São Paulo) August 1, 2017