Skip to content

The Association of Classic Serotonergic Psychedelic Use and Intention of Future Use with Nature Relatedness

Marcio S. C. Longo, Bheatrix Bienemann, Marco Multedo, Marco Aurélio Negreiros, Eduardo Ekman Schenberg, Daniel C Mograbi

Journal of Psychoactive Drugs August 19, 2022 DOI: 10.1080/02791072.2022.2112788 (opens in new tab)

Relevant Not relevant

Study at a glance

AI-extracted from the abstract
Characteristics Cross-sectional survey Peer reviewed
Population General population in Brazil
Topics Ayahuasca Cannabis MDMA Psilocybin Serotonin
Keywords Hallucinogen Population Analysis of variance Psychoactive substance Clinical psychology Association psychology Environmental health Psychotherapist
Citations 10
Key findings Only ayahuasca/DMT past and current use remained positively associated with nature relatedness after controlling for sociodemographic variables.

Abstract

This study sought to investigate the effects of different substances on nature relatedness (NR) in the general population. An online cross-sectional survey done in Brazil investigated use of ayahuasca/DMT, psilocybe mushrooms, LSD, MDMA/ecstasy, cocaine, cannabis, and alcohol. NR was assessed using the short-form version of the nature related scale (NR-6). One-way analysis of variance (ANOVA) was used to assess group differences between substance naïve-individuals, past users, and current users of each substance. Regression models were used including all the substances and subsequently, sociodemographic variables. ANOVAs with substances which showed significantly higher NR-6 scores in the regression model were used in order to assess the effect of intention of future use on NR. ANOVAs indicated higher NR in users of classic serotonergic psychedelics (ayahuasca/DMT, psilocybe mushrooms, LSD), cannabis, and MDMA/ecstasy. Regression models showed that current use of ayahuasca/DMT and psilocybe mushrooms, and past use of LSD had a positive association with NR. When sociodemographic variables were added, only ayahuasca/DMT past and current use were positively associated with NR. Intention of future use was only significantly associated with NR in individuals who reported intention of future use of psilocybe mushrooms.

Comparable studies

Other cross-sectional and survey studies on serotonin, most cited first.

Study Year Design Participants
Reducedin vivobinding to the serotonin transporter in the cerebral cortex of MDMA (‘ecstasy’) users Male regular ecstasy users and well-matched controls 1999 Cross-sectional association study n = 20
Cerebral1H MRS alterations in recreational 3,4-methylenedioxymethamphetamine (MDMA, ?ecstasy?) users Recreational MDMA users and normal subjects 1999 Cross-sectional study n = 59
Evidence for a common biological basis of the absorption trait, hallucinogen effects, and positive symptoms: Epistasis between 5-HT2a and COMT polymorphisms 95 male and 241 female subjects 2005 Cross-sectional genetic association study n = 336
Recreational use of psychedelics is associated with elevated personality trait openness: Exploration of associations with brain serotonin markers. 10 psychedelic-preferring recreational users, 14 MDMA-preferring users, and 21... 2019 Cross-sectional observational study n = 45
In Vivo Imaging of Cerebral Serotonin Transporter and Serotonin2A Receptor Binding in 3,4-Methylenedioxymethamphetamine (MDMA or “Ecstasy”) and Hallucinogen Users 2011 Cross-sectional study

Citations in the library

Cited by 10

and 5 more in the library

Cites 26

and 21 more in the library

Related reading

Explore topics

Ayahuasca Cannabis MDMA Psilocybin Serotonin LSD