Psychological effects and subjective experiences of ayahuasca rituals in participants of two neoshamanic centers of Uruguay
Ismael Apud, Juan Scuro, Ignacio Carrera, Andrés Oliveri
Journal of Psychedelic Studies September 2, 2022 DOI: 10.1556/2054.2022.00202 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Mixed qualitative-quantitative study Peer reviewed |
|---|---|
| Population | Participants in ayahuasca ceremonies at two neoshamanic centers in Uruguay |
| Intervention | Ayahuasca |
| Topics | Ayahuasca |
| Keywords | Cognition Perception Affect linguistics Clinical psychology Qualitative research Hallucinogen Rating scale Qualitative property Developmental psychology |
| Citations | 6 |
| Key findings | Significant medium-sized differences in affect, cognition, and perception were found between the two neoshamanic groups, with qualitative reports of more frequent and complex experiences in the group scoring higher on those variables. |
Abstract
Abstract Background Ayahuasca's psychological and subjective effects were compared in rituals of two neoshamanic groups in Uruguay.
Aims: Compare, describe and analyze psychological effects and subjective experiences of ayahuasca ceremonies in two different groups: a psychospiritual holistic center, and a center specialized in substance use disorder's treatment.
Methods: A mixed qualitative-quantitative study was conducted, using the Hallucinogen Rating Scale for measuring psychological effects, and in-depth interviews for the description of ayahuasca subjective experiences. Data from both techniques were compared, analyzing convergences and differences.
Results: When comparing the two neoshamanic groups, significant differences with a medium-size effect were found in the psychological variables Affect ( r = 0.47), Cognition ( r = 0.36) and Perception ( r = 0.36). The qualitative descriptions of ayahuasca experiences in the group with higher scores in those variables showed more frequent and complex experiences of emotional, cognitive, and perceptive content. Dissimilar results were found when comparing Intensity and Somaesthetic domains, with no significant results in the quantitative part, while in the qualitative part intensity was reported as “soft” in one group, and corporal experiences (e.g., purging effects) were especially manifested.
Conclusions: Stronger subjective experiences and higher psychological effects may be related to differences in the dosage and the setting of the centers. Emotional, cognitive, and perceptive psychological effects of ayahuasca rituals measured by the Hallucinogen Rating Scale, seem to be associated with more frequent and complex subjective experiences in the mentioned domains. Qualitative group differences in corporal alterations and the overall intensity of the experience differed from non-significant results of the quantitative part of the study.
Comparable studies
Other qualitative studies on ayahuasca, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| The antipodes Of the mind Indigenous people, shamans, members of different religious sects using Ayahuasca, and... | 2002 | Qualitative study | |
| Drug Tourism or Spiritual Healing? Ayahuasca Seekers in Amazonia Westerners participating in an ayahuasca retreat in Amazonia | 2005 | Qualitative study | |
| Therapeutic Effects of Ritual Ayahuasca Use in the Treatment of Substance Dependence—Qualitative Results Therapists, expert researchers, and individuals who underwent ayahuasca-assisted... | 2014 | Qualitative study | n = 29 |
| Nourishing the Spirit: Exploratory Research on Ayahuasca Experiences along the Continuum of Recovery from Eating Disorders Individuals previously diagnosed with an eating disorder | 2017 | Qualitative study | n = 16 |
| Exploring ayahuasca‐assisted therapy for addiction: A qualitative analysis of preliminary findings among an Indigenous community in Canada Indigenous adults in Canada who participated in ayahuasca-assisted ceremonial retreats | 2019 | Qualitative study | n = 11 |
Citations in the library
Cited by 3
- The Hallucinogen Rating Scale: Updated Factor Structure in a Large, Multistudy Sample. Biological Psychiatry Global Open Science March 1, 2025
- Ayahuasca, Personality and Acute Psychological Effects in Neo-Shamanic and Religious Settings in Uruguay. Journal of Psychoactive Drugs 2023
- Predicting and exploring ayahuasca effects: Perception, mind-wandering, and EEG oscillations Journal of Psychopharmacology December 4, 2025
Cites 32
- The Subjective Effects of Psychedelics Are Necessary for Their Enduring Therapeutic Effects. ACS Pharmacology & Translational Science December 10, 2020
- Dose-Response Study of N,N-Dimethyltryptamine in Humans Archives of General Psychiatry February 1, 1994
- Monoamine oxidase inhibitors in South American hallucinogenic plants: Tryptamine and β-carboline constituents of Ayahuasca Journal of Ethnopharmacology April 1, 1984
- Ayahuasca-Assisted Therapy for Addiction: Results from a Preliminary Observational Study in Canada Current Drug Abuse Reviews June 1, 2013
- Subjective effects and tolerability of the South American psychoactive beverage Ayahuasca in healthy volunteers Psychopharmacology February 22, 2001
and 27 more in the library