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LSD Hallucinations: From Ergot to Electric Kool-Aid

Ronald K. Siegel

Journal of Psychoactive Drugs October 1, 1985 DOI: 10.1080/02791072.1985.10524329 (opens in new tab) via OpenAlex

Summary

AI-generated from the abstract

LSD, derived from ergot alkaloids, produces hallucinations by interfering with serotonin neurotransmission in the brain. The article traces the history of LSD from its synthesis by Albert Hofmann in 1938 through its use in psychiatric research and later as a recreational drug in the 1960s counterculture. It describes how LSD's effects vary with dose, setting, and the user's psychological state, and notes that while early research suggested therapeutic potential, political and cultural controversies led to its prohibition and the end of most clinical studies.

Study at a glance

Characteristics Historical analysis Peer reviewed
Keywords Psychology Psychiatry Medicine Anesthesia
Citations 9
Key finding Argues that LSD's trajectory from psychiatric research to counterculture symbol was shaped by both its pharmacological properties and the social context of the 1960s.

Abstract

(1985). LSD Hallucinations: From Ergot to Electric Kool-Aid. Journal of Psychoactive Drugs: Vol. 17, LSD in Retrospect, pp. 247-256.

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