Well-being, problematic alcohol consumption and acute subjective drug effects in past-year ayahuasca users: a large, international, self-selecting online survey
Will Lawn, Jaime E. C. Hallak, José Alexandre S. Crippa, Rafael G. Dos Santos, Lilla Porffy, Monica J Barratt, Jason Ferris, Adam Winstock, Celia J. A. Morgan
Scientific Reports November 3, 2017 DOI: 10.1038/s41598-017-14700-6 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Cross-sectional survey Randomized Longitudinal Peer reviewed |
|---|---|
| Sample size | 96,901 |
| Population | Online, self-selecting global respondents who reported drug use patterns |
| Topics | Ayahuasca LSD |
| Keywords | Hallucinogen Demographics |
| Citations | 78 |
| Key findings | Ayahuasca users reported greater well-being and less problematic drinking than classic psychedelic users, but both psychedelic groups reported more problematic drinking than non-psychedelic drug users. |
Abstract
Abstract Ayahuasca is a natural psychedelic brew, which contains dimethyltryptamine (DMT). Its potential as a psychiatric medicine has recently been demonstrated and its non-medical use around the world appears to be growing. We aimed to investigate well-being and problematic alcohol use in ayahuasca users, and ayahuasca’s subjective effects. An online, self-selecting, global survey examining patterns of drug use was conducted in 2015 and 2016 (n = 96,901). Questions were asked about: use of ayahuasca, lysergic acid diethylamide (LSD) and magic mushrooms; demographics, current well-being and past-year problematic alcohol use of past-year ayahuasca users and comparison drug users; and subjective effects of ayahuasca and comparison drugs. Ayahuasca users (n = 527) reported greater well-being than both classic psychedelic users (n = 18,138) and non-psychedelic drug-using respondents (n = 78,236). Ayahuasca users reported less problematic drinking than classic psychedelic users, although both groups reported greater problematic drinking than the other respondents. Ayahuasca’s acute subjective effects usually lasted for six hours and were most strongly felt one hour after consumption. Within our online, self-selecting survey, ayahuasca users reported better well-being than comparison groups and less problematic drinking than classic psychedelic users. Future longitudinal studies of international samples and randomised controlled trials are needed to dissect the effects of ayahuasca on these outcomes.