How LSD Originated
Journal of Psychedelic Drugs January 1, 1979 DOI: 10.1080/02791072.1979.10472092 (opens in new tab) via OpenAlex
Summary
AI-generated from the abstractLSD was first synthesized in 1938 by Albert Hofmann at Sandoz Laboratories in Switzerland while he was investigating ergot alkaloids for potential medicinal uses. Hofmann accidentally discovered its psychoactive effects in 1943 after unintentionally absorbing a small amount through his skin, leading to the first intentional self-experiment with the substance. The article recounts the historical circumstances of LSD's discovery, including Hofmann's systematic exploration of the compound's properties and his detailed accounts of the subjective experiences during his initial trials. The narrative traces the compound's development from a laboratory curiosity to a substance that would later influence psychiatry and culture.
Study at a glance
| Characteristics | Historical analysis Peer reviewed |
|---|---|
| Keywords | Psychology |
| Citations | 108 |
| Key finding | Presents Albert Hofmann's firsthand narrative of synthesizing LSD-25 in 1938 and discovering its psychoactive properties in 1943. |
Abstract
(1979). How LSD Originated. Journal of Psychedelic Drugs: Vol. 11, Innovative Approached to Drug Abuse Treatment, pp. 53-60.